Ouabain相关论文
Canine cancers develop in immunocompetent environments and share many similar features observed in human cancers,such as......
Proliferating cell nuclear antigen involved in the repair process of ouabain-induced brain damage in
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毒毛花苷G种内收蛋白对高血压中纳的特殊干预研究( the Ouabain and Adducin for Specific Intervention on Sodium in Hypertensio......
Whether La3+ can enter human peripheral blood lymphocytes by the Na+/Ca2+ exchanger or not and the effect of La3+ on the......
Comparative study of renal sodium transport between ouabain-hypertensive rats and ouabain-nonhyperte
Objective: To compare renal sodium transport, using fractional excretions of lithium(FEii)as a marker of proximal tubule......
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Objective:To investigate the ouabains effects on the ultrastructure and function of the rat heart. Methods: Male Sprague......
Comparative study of renal sodium transport between ouabain-hypertensive rats and ouabain-nonhyperte
Objective: To compare renal sodium transport, using fractional excretions of lithium(FEii)as a marker of proximal tubule......
研究小檗胺(Ber)对氯化钾(KC1)和哇巴因(Oua)诱导的家兔血管平滑肌细胞(VSMC)内游离钙([Ca(2+)]i)的影响。培养的VSMC以荧光探针Fluo-3/AM负载,......
Na^+/K^+-ATP酶是存在于几乎所有真核生物细胞膜上的一种跨膜蛋白质,是维持细胞内环境离子稳定及细胞生命活动重要的蛋白酶。其主要......
目的:建立SD大鼠腹腔注射Ouabain诱导的弱精子症动物模型。方法:健康性成熟SD雄性大鼠40只,随机分为对照组(生理盐水,n=10),低剂量......
在体外培养的条件下,大鼠晶体中 Na K-ATPase 可被1mmol/L ouabain 所抑制,抑制的程度随着 ouabain 作用的时间而加强。鼠晶体被 o......
通过对钠钾ATP酶及其与哇巴因的复合物进行分子动力学模拟来研究哇巴因对该酶构象的影响,首先利用对接得到复合物,然后在相同环境......
,Gene Expression Analysis of Human Vascular Endothelial Cells Treated by Ouabain in Pathological Con
Objectives To study the gene expression of human vascular endothelial cells (HUVEC) treated by ouabain in pathological c......
Aim: To examine the time- and dose-dependent effects of ouabain on human umbilical vein endothelial cells (HUVEC) in viv......
Aim: To investigate the ouabain’s effects on cardiac remodeling in rats. Methods:Male Sprague-Dawley rats were treated ......
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,Discovery of N-(3,5-bis(1-pyrrolidylmethyl)-4-hydroxybenzyl)-4-methoxybenzenesulfamide (sulcardine)
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,Ouabain impairs cancer metabolism and activates AMPK-Src signaling pathway in human cancer cell lin
In addition to the well-known cardiotonic effects,cardiac glycosides (CGs) produce potent anticancer effects with variou......
Proliferating cell nuclear antigen involved in the repair process of ouabain-induced brain damage in
Background Ouabain is a mammalian adrenocortical hormone that is involved in the pathogenesis of hypertension by inhibit......
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Study on the Interferation of the Concentration of Free Calcium in Peripheral Human Lymphocyte by Lo
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
利用荧光浓度指示剂fura-2研究了La~(3+)能否利用Na~+/Ca~(2+)交换系统进入人外周血淋巴细胞以及La~(3+)对Na+/Ca~(2+)交换的影响.......
目的 观察哇巴因联合Na~+/K~+-ATP酶(钠泵)α1亚单位小干扰RNA(siRNA)对人肝癌HepG2细胞增殖和细胞周期的影响.方法 分析人肝癌临......
目的:观察不同浓度哇巴因(ouabain,OUA)对大鼠离体心功能的影响。方法:SD雄性大鼠随机分成7组(n=6):正常组(NC组),OUA 10~(-9)mol/......
Background Ouabain, a cardiac glycoside that specifically binds to Na/K-ATPase and inhibits its activity, was applied to......
BACKGROUND:It has been previously shown that intrathecal administration of either ouabain or neostigmine can produce ant......
The Ly5.1 mouse,also termed B6.SJL-Ptprca Pepcb/BoyJ,is a congenic strain widely used as a recipient in animal studies o......
Study on the Interferation of the Concentration of Free Calcium in Peripheral Human Lymphocyte by Lo
The effect of penicillin on the human peripheral lymphocytes was studied by steady fluorescent technique and ratiometric......
Whether La3+ can enter human peripheral blood lymphocytes by the Na+/Ca2+ exchanger or not and the effect of La3+on the......
目的研究哇巴因对小鼠内耳神经胶质细胞的影响,为干细胞移植治疗感音神经性聋的研究奠定基础。方法成年雌性SPF级CBA/J小鼠60只,随......
目的:评价特异性钠泵抑制剂哇巴因在体外对非小细胞肺癌A549细胞增殖与死亡的影响。方法:利用细胞培养技术,采用MTT法、流式细胞技术......
Ouabain-resistant phenomenon and changes of transmembrane ion transport in essential hypertensives w
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Ouabain-resistant phenomenon and changes of transmembrane ion transport in essential hypertensives w
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目的建立一种慢性洋地黄中毒的动物模型。方法大鼠腹腔内注射中毒剂量的哇巴因0.045mg/Kg.d连续两周,观察动物体重、心电图、心脏......
目的:观察慢性洋地黄中毒对大鼠心室肌起搏通道基因表达的影响。方法:给予大鼠腹腔内注射哇巴因0.045 mg/(kg·d)连续两周。取大鼠......
目的研究哇巴因对自发性高血压大鼠(SHR)和Wistar-Kyoto(WKY)大鼠动脉平滑肌细胞(ASMCs)分泌血管紧张素Ⅱ(AngⅡ)和心钠素(ANP)的影响及其可......
目的 沙鼠耳蜗圆窗应用毒毛旋花甙G(Ouabain),观察沙鼠蜗外电诱发听性脑干反应(EABR)的变化。方法显微镜下将浸有50μl Ouabain(1mM)的明......
本实验研究了MgSo_4对实验性心律失常的作用。结果表明MgSO_4:可对抗哇巴因诱发豚鼠心律失常;可减少氯仿对小鼠的致颤率;能减少乌......
本文采用细胞内固定微电极技术观察了沙棘总黄酮对哇巴因诱发的心律失常模型和豚鼠心室肌正常电机械活动的影响。结果表明,沙棘总......
通过给予大鼠外源性哇巴因,观察其对血压的影响,并同地高辛进行对比研究,发现长期给予小剂量哇巴因可引起大鼠血压明显升高,而地高辛无......
目的 观察槲皮素抗实验性心律失常的作用,并探讨其可能机制。方法 应用乌头碱,氯化钙制备大鼠心律失常模型,哇巴因制备豚鼠心律失常模......
目的观察硫化氢对哇巴因诱发触发性心律失常的作用,并进一步探讨其可能的作用机制。方法采用SD大鼠,建立离体心脏Langendorff主动脉......
目的探讨哇巴因特异性调节Na+/K+-ATP酶表达的作用机制。方法用相同的实验条件作用于人肾近曲小管上皮细胞株(HKCs)、人乳腺癌细胞株(MC......
在高钾去极化使钠通道完全失活的条件下,哇巴因无增强豚鼠乳头状肌收缩力的作用;在奎尼丁使钠通道部分失活的条下,则表现出一定的......